STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
P2RY10P2Y receptor family member 10. (388 aa)    
Predicted Functional Partners:
GDPD1
Glycerophosphodiester phosphodiesterase domain containing 1.
      
 0.710
GDPD3
Glycerophosphodiester phosphodiesterase domain containing 3.
      
 0.650
GPR22
G protein-coupled receptor 22.
      
 0.635
PTGER1
Prostaglandin E2 receptor EP1 subtype; Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(q) proteins which activate a phosphatidylinositol-calcium second messenger system. May play a role as an important modulator of renal function. Implicated the smooth muscle contractile response to PGE2 in various tissues (By similarity). Belongs to the G-protein coupled receptor 1 family.
   
  
 0.621
GPR142
G-protein coupled receptor 142; Belongs to the G-protein coupled receptor 1 family.
      
 0.612
GNA15
G protein subunit alpha 15.
   
 
 0.602
PTH2R
Parathyroid hormone 2 receptor; Belongs to the G-protein coupled receptor 2 family.
      
 0.563
BTK
Tyrosine-protein kinase.
   
 
  0.541
GRK2
G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.
   
 
 0.535
RAB15
RAB15, member RAS oncogene family.
   
  
 0.529
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.