STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PRKCSHProtein kinase C substrate 80K-H. (537 aa)    
Predicted Functional Partners:
GANAB
Glucosidase II alpha subunit; Belongs to the glycosyl hydrolase 31 family.
   
 0.997
CCDC167
Coiled-coil domain containing 167.
      
 0.875
RSRC2
Arginine and serine rich coiled-coil 2.
      
 0.857
FIZ1
FLT3 interacting zinc finger 1.
    
 
 0.841
ZNF784
Zinc finger protein 784.
    
 
 0.841
AKT1S1
AKT1 substrate 1.
   
  
 0.790
RCOR3
REST corepressor 3.
   
  
 0.762
HSP90B1
Endoplasmin; Molecular chaperone that functions in the processing and transport of secreted proteins (By similarity). When associated with CNPY3, required for proper folding of Toll-like receptors (By similarity). Functions in endoplasmic reticulum associated degradation (ERAD) (By similarity). Has ATPase activity. Belongs to the heat shock protein 90 family.
   
 0.751
ALG5
ALG5 dolichyl-phosphate beta-glucosyltransferase.
      
 0.688
OLFM2
Olfactomedin 2.
      
 0.680
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
Server load: low (16%) [HD]