STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ANP32AAcidic leucine-rich nuclear phosphoprotein 32 family member A; Implicated in a number of cellular processes, including proliferation, differentiation, caspase-dependent and caspase- independent apoptosis, suppression of transformation (tumor suppressor), inhibition of protein phosphatase 2A, regulation of mRNA trafficking and stability in association with ELAVL1, and inhibition of acetyltransferases as part of the INHAT (inhibitor of histone acetyltransferases) complex. Plays a role in E4F1-mediated transcriptional repression (By similarity). (306 aa)    
Predicted Functional Partners:
XPO1
Exportin 1.
   
 0.861
SET
Uncharacterized protein; Belongs to the nucleosome assembly protein (NAP) family.
   
 0.856
NUP214
Nucleoporin 214.
     
 0.804
TNFSF13
TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family.
     
  0.800
DDX17
DEAD-box helicase 17; Belongs to the DEAD box helicase family.
   
 
 0.716
H2AFZ
Histone H2A; Belongs to the histone H2A family.
   
 
 0.647
J9NWQ8_CANLF
Histone H2A; Belongs to the histone H2A family.
   
 
 0.646
H2AZ2
Histone H2A; Belongs to the histone H2A family.
   
 
 0.646
ELAVL1
ELAV-like protein; Belongs to the RRM elav family.
   
 0.607
CIP2A
Cell proliferation regulating inhibitor of protein phosphatase 2A.
   
  
 0.603
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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