STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SLC5A11Solute carrier family 5 member 11; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (673 aa)    
Predicted Functional Partners:
SLC2A12
Solute carrier family 2 member 12; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
   
  
 0.665
SLC13A4
Solute carrier family 13 member 4.
   
  
 0.660
ENSCAFP00000040898
Cathepsin L1 Cathepsin L1 heavy chain Cathepsin L1 light chain.
      
 0.644
SLC1A4
Solute carrier family 1 member 4.
   
  
 0.607
SLC43A2
Solute carrier family 43 member 2.
   
  
 0.593
SLC7A8
Uncharacterized protein.
   
  
 0.584
SLC2A1
Solute carrier family 2, facilitated glucose transporter member 4; Insulin-regulated facilitative glucose transporter, which plays a key role in removal of glucose from circulation. Response to insulin is regulated by its intracellular localization: in the absence of insulin, it is efficiently retained intracellularly within storage compartments in muscle and fat cells. Upon insulin stimulation, translocates from these compartments to the cell surface where it transports glucose from the extracellular milieu into the cell.
   
 
 0.581
STC1
Stanniocalcin 1.
      
 0.574
SLC7A2
Solute carrier family 7 member 2.
   
  
 0.566
SLC2A5
Solute carrier family 2 member 5; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
   
  
 0.546
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.