STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
S100A6S100 calcium binding protein A8; Belongs to the S-100 family. (191 aa)    
Predicted Functional Partners:
CACYBP
Calcyclin binding protein.
   
 
 0.890
ANXA2
Annexin A2; Calcium-regulated membrane-binding protein whose affinity for calcium is greatly enhanced by anionic phospholipids. It binds two calcium ions with high affinity. May be involved in heat-stress response. Inhibits PCSK9-enhanced LDLR degradation, probably reduces PCSK9 protein levels via a translational mechanism but also competes with LDLR for binding with PCSK9; Belongs to the annexin family.
   
 
 0.735
S100A10
S_100 domain-containing protein; Belongs to the S-100 family.
   
 
 0.728
S100A13
S100 calcium binding protein A13; Belongs to the S-100 family.
   
  
 0.727
S100A11
Protein S100; Belongs to the S-100 family.
   
 
0.708
S100B
Protein S100; Belongs to the S-100 family.
   
 
 0.707
S100A16
Protein S100; Belongs to the S-100 family.
   
 
 0.707
AGER
Advanced glycosylation end product-specific receptor variant C.
    
 
 0.685
ANXA1
Annexin.
   
 
 0.684
LOC100687983
Uncharacterized protein.
   
 
 0.664
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.