STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SMG8SMG8 nonsense mediated mRNA decay factor. (991 aa)    
Predicted Functional Partners:
SMG9
SMG9 nonsense mediated mRNA decay factor.
    
 0.999
SMG1
SMG1 nonsense mediated mRNA decay associated PI3K related kinase; Belongs to the PI3/PI4-kinase family.
   
 0.992
SMG5
SMG5 nonsense mediated mRNA decay factor.
   
 
 0.938
UPF2
UPF2 regulator of nonsense mediated mRNA decay.
   
  
 0.870
ANKFN1
Ankyrin repeat and fibronectin type III domain containing 1.
   
  
 0.803
SMG7
SMG7 nonsense mediated mRNA decay factor.
     
 0.774
DDX20
DEAD-box helicase 20.
   
  
 0.767
UPF1
UPF1 RNA helicase and ATPase.
    
 
 0.750
DCP1A
Decapping mRNA 1A.
   
 
 0.747
SMG6
SMG6 nonsense mediated mRNA decay factor.
     
 0.747
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.