STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
UNC79Unc-79 homolog, NALCN channel complex subunit. (2644 aa)    
Predicted Functional Partners:
UNC80
Unc-80 homolog, NALCN channel complex subunit.
   
 0.997
NALCN
Sodium leak channel, non-selective.
   
 0.991
FAM155B
Family with sequence similarity 155 member B.
    
 
 0.989
FAM155A
Family with sequence similarity 155 member A.
    
 
 0.989
TPC3
Uncharacterized protein.
   
 
 0.829
CATSPER3
Cation channel sperm associated 3.
   
 
 0.823
CATSPER2
Cation channel sperm associated 2.
   
 
 0.818
ANO4
Anoctamin.
      
 0.814
LHFPL4
LHFPL tetraspan subfamily member 4.
   
  
 0.808
CACNA1A
Voltage-dependent P/Q-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q- type calcium currents.
   
 
 0.807
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.