STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PAPOLAPoly(A) polymerase; Polymerase that creates the 3'-poly(A) tail of mRNA's. (749 aa)    
Predicted Functional Partners:
SYMPK
Symplekin.
   
 0.977
CPSF2
Cleavage and polyadenylation specificity factor subunit 2.
   
 0.969
CPSF1
Cleavage and polyadenylation specific factor 1.
   
 0.967
FIP1L1
Factor interacting with PAPOLA and CPSF1.
   
 0.961
WDR33
WD repeat domain 33.
   
 0.951
CPSF3
Cleavage and polyadenylation specific factor 3.
   
 0.950
CSTF3
Cleavage stimulation factor subunit 3.
   
 0.950
CPSF4
Cleavage and polyadenylation specific factor 4.
    
 0.937
PAPOLG
Poly(A) polymerase gamma.
  
 
0.910
RBBP6
RB binding protein 6, ubiquitin ligase.
   
 
 0.909
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.