STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BCL11BBAF chromatin remodeling complex subunit BCL11B. (917 aa)    
Predicted Functional Partners:
SATB2
DNA-binding protein SATB.
   
 
 0.754
TBR1
T-box brain transcription factor 1.
    
 
 0.721
SATB1
SATB homeobox 1.
   
 
 0.598
NKAP
NFKB activating protein.
      
 0.575
TCF7
Transcription factor 7.
   
 
 0.567
JDP2
Jun dimerization protein 2.
    
 
 0.545
GATA3
GATA binding protein 3.
    
 
 0.544
CHD4
Chromodomain helicase DNA binding protein 4.
   
 
 0.528
CUX1
Homeobox protein cut-like 1; Probably has a broad role in mammalian development as a repressor of developmentally regulated gene expression. May act by preventing binding of positively-activing CCAAT factors to promoters. Component of nf-munr repressor; binds to the matrix attachment regions (MARs) (5' and 3') of the immunoglobulin heavy chain enhancer. Represses T-cell receptor (TCR) beta enhancer function by binding to MARbeta, an ATC-rich DNA sequence located upstream of the TCR beta enhancer (By similarity).
    
 
 0.527
DLX1
Distal-less homeobox 1.
    
 
 0.521
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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