STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GM2AGM2 ganglioside activator. (196 aa)    
Predicted Functional Partners:
HEXA
Beta-hexosaminidase.
    
 
 0.742
GLB1
Beta-galactosidase; Cleaves beta-linked terminal galactosyl residues from gangliosides, glycoproteins, and glycosaminoglycans. Belongs to the glycosyl hydrolase 35 family.
   
 
 0.738
MEP1B
Meprin A subunit.
      
 0.721
HEXB
Hexosaminidase subunit beta.
    
 
 0.635
SHPRH
SNF2 histone linker PHD RING helicase.
   
  
 0.599
HAO2
Hydroxyacid oxidase 2.
   
  
 0.589
ARSA
Arylsulfatase A.
   
  
 0.578
NPC2
NPC intracellular cholesterol transporter 2.
   
  
 0.578
DOC2A
Double C2 domain alpha.
      
 0.565
GALNS
N-acetylgalactosamine-6-sulfatase.
   
  
 0.565
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
Server load: low (10%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.