STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KNOP1Lysine rich nucleolar protein 1. (457 aa)    
Predicted Functional Partners:
WDR38
WD repeat domain 38.
    
 
 0.774
IGSF6
Immunoglobulin superfamily member 6.
      
 0.731
FAM133B-2
Family with sequence similarity 133 member B.
      
 0.730
FAM133B
Family with sequence similarity 133 member B.
      
 0.730
IRS4
Insulin receptor substrate 4.
  
   
 0.654
CHRNG
Cholinergic receptor nicotinic gamma subunit.
      
 0.605
DRG1
Developmentally regulated GTP binding protein 1.
      
 0.515
ENSCAFP00000043973
Uncharacterized protein.
      
 0.515
CHAC1
Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family.
      
 0.501
MFSD4B
Major facilitator superfamily domain containing 4B.
      
 0.480
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.