STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TMC5Transmembrane channel-like protein. (999 aa)    
Predicted Functional Partners:
ZNF683
Zinc finger protein 683.
   
 
 0.876
SPATS1
Spermatogenesis associated serine rich 1.
   
  
 0.875
DNAJC14
J domain-containing protein.
      
 0.874
KAT6B
Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.
    
 
 0.873
KNTC1
Kinetochore associated 1.
      
 0.816
HPS5
Hermansky-Pudlak syndrome 5 protein homolog; May regulate the synthesis and function of lysosomes and of highly specialized organelles, such as melanosomes and platelet dense granules.
      
 0.789
SALL4
Spalt like transcription factor 4.
      
 0.608
ESCO1
Establishment of sister chromatid cohesion N-acetyltransferase 1.
    
 
 0.601
AGPS
Alkylglycerone-phosphate synthase; Catalyzes the exchange of an acyl for a long-chain alkyl group and the formation of the ether bond in the biosynthesis of ether phospholipids; Belongs to the FAD-binding oxidoreductase/transferase type 4 family.
    
 
 0.577
KCNH8
Potassium voltage-gated channel subfamily H member 8.
   
  
 0.532
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.