STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ASPGAsparaginase. (849 aa)    
Predicted Functional Partners:
TMEM121
Transmembrane protein 121.
      
 0.671
UOX
Uricase; Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin; Belongs to the uricase family.
      
 0.624
RD3L
Retinal degeneration 3 like.
      
 0.560
NAGS
N-acetylglutamate synthase.
      
 0.499
CPS1
Carbamoyl-phosphate synthase 1.
    
 
 0.492
SLC19A2
Solute carrier family 19 member 2.
      
 0.480
DCTD
dCMP deaminase.
   
  
 0.474
S1PR3
Sphingosine-1-phosphate receptor 3; Belongs to the G-protein coupled receptor 1 family.
    
 
 0.471
SIVA1
Apoptosis regulatory protein Siva; Induces CD27-mediated apoptosis. Inhibits BCL2L1 isoform Bcl- x(L) anti-apoptotic activity. Inhibits activation of NF-kappa-B and promotes T-cell receptor-mediated apoptosis.
    
 
 0.468
ADA
Adenosine deaminase.
   
 
 0.454
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.