STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
UBE2AUbiquitin conjugating enzyme E2 A; Belongs to the ubiquitin-conjugating enzyme family. (329 aa)    
Predicted Functional Partners:
UBA1
Ubiquitin like modifier activating enzyme 1; Belongs to the ubiquitin-activating E1 family.
   
 0.952
RNF20
E3 ubiquitin protein ligase; Belongs to the BRE1 family.
   
 0.856
RNF40
E3 ubiquitin protein ligase; Belongs to the BRE1 family.
   
 0.856
RAD18
RAD18 E3 ubiquitin protein ligase.
   
 
 0.848
UBA7
Ubiquitin like modifier activating enzyme 7; Belongs to the ubiquitin-activating E1 family.
    
 0.847
UBE2V1
Ubiquitin conjugating enzyme E2 V1.
   
 0.825
UBB
Ubiquitin B.
   
 0.800
UBA6
Ubiquitin like modifier activating enzyme 6.
   
 0.797
RPS27A
Ubiquitin-like domain-containing protein.
   
 0.784
ENSCAFP00000050780
Ubiquitin-like domain-containing protein.
   
 0.781
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.