STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RHBDL3Rhomboid-related protein 3; May be involved in regulated intramembrane proteolysis and the subsequent release of functional polypeptides from their membrane anchors; Belongs to the peptidase S54 family. (367 aa)    
Predicted Functional Partners:
RHOT2
WD repeat domain 90.
 
 
 
 0.657
MAGI3
Membrane associated guanylate kinase, WW and PDZ domain containing 3.
  
 
 0.598
CASK
Calcium/calmodulin dependent serine protein kinase; Belongs to the MAGUK family.
   
 
 0.581
CAPN12
Calpain 12; Belongs to the peptidase C2 family.
   
 
 0.565
RHBDD3
Rhomboid domain containing 3.
      
 0.564
LRGUK
Leucine rich repeats and guanylate kinase domain containing.
  
 
 0.541
FGF11
Fibroblast growth factor; Belongs to the heparin-binding growth factors family.
   
 
 0.530
TEKT1
Tektin-1.
    
 
 0.527
RHBDD1
Rhomboid domain containing 1.
      
 0.515
PARL
Presenilin associated rhomboid like.
      
 0.450
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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