STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ZBP1Z-DNA binding protein 1. (242 aa)    
Predicted Functional Partners:
RIPK3
Protein kinase domain-containing protein.
    
 0.968
RIPK1
Receptor interacting serine/threonine kinase 1.
    
 0.965
IRF3
Interferon regulatory factor 3.
   
 0.954
TBK1
TANK binding kinase 1.
   
 0.940
IKBKE
Inhibitor of nuclear factor kappa B kinase subunit epsilon.
   
 0.927
LOC488622
Uncharacterized protein.
   
  
 0.846
DHX33
DEAH-box helicase 33.
      
 0.749
UBA7
Ubiquitin like modifier activating enzyme 7; Belongs to the ubiquitin-activating E1 family.
   
    0.665
RTP4
Receptor transporter protein 4.
   
    0.665
IFI44L
Interferon induced protein 44 like.
   
  
 0.663
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.