Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
NDE1NudE neurodevelopment protein 1. (335 aa)    
Predicted Functional Partners:
NDEL1
NudE neurodevelopment protein 1 like 1.
   
 
 0.942
PAFAH1B1
Platelet-activating factor acetylhydrolase IB subunit alpha; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. Required during brain development for the proliferation of neuronal precursors and the migration of newly formed neurons from the ven [...]
    
 
 0.903
DISC1
DISC1 scaffold protein.
    
 
 0.823
CENPF
Centromere protein F.
   
 
 0.783
TSNARE1
t-SNARE domain containing 1.
    
 
 0.782
DYNC1I2
Dynein cytoplasmic 1 intermediate chain 2.
    
 
 0.755
DIXDC1
DIX domain containing 1.
    
 
 0.680
WDR62
WD repeat domain 62.
      
 0.591
PSMA4
Proteasome subunit alpha 4.
      
 0.591
TBC1D31
TBC1 domain family member 31.
    
 
 0.586
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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