STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CAPSCalcyphosin; Calcium-binding protein. May play a role in cellular signaling events (Potential). (189 aa)    
Predicted Functional Partners:
CATIP
Ciliogenesis associated TTC17 interacting protein.
   
   0.817
AK8
Adenylate kinase 8; Belongs to the adenylate kinase family.
   
    0.805
VWA2
Von Willebrand factor A domain containing 2.
   
   0.709
LRP5
Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family.
      
 0.696
COL6A3
Collagen type VI alpha 3 chain.
   
   0.686
LMBRD2
LMBR1 domain containing 2.
 
 
  
 0.644
LOC610540
Pulmonary surfactant-associated protein A; In presence of calcium ions, it binds to surfactant phospholipids and contributes to lower the surface tension at the air- liquid interface in the alveoli of the mammalian lung and is essential for normal respiration. Enhances the expression of MYO18A/SP-R210 on alveolar macrophages; Belongs to the SFTPA family.
   
 
 0.624
PNPLA1
PNPLA domain-containing protein.
   
  
 0.605
CIB1
Calcium and integrin binding 1.
   
 
 0.571
RSPH1
Radial spoke head 1 homolog.
   
  
 0.570
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.