STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MPPE1Metallophosphoesterase 1. (391 aa)    
Predicted Functional Partners:
PSMB5
Proteasome subunit beta.
 
      0.890
IMPA2
Inositol-1-monophosphatase.
   
  
 0.876
VAPA
VAMP associated protein A.
      
 0.677
NDUFV2
NADH dehydrogenase [ubiquinone] flavoprotein 2.
      
 0.673
GNAL
G protein subunit alpha L.
      
 0.666
MYO5B
Myosin VB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
   
  
 0.653
PGAP3
Post-GPI attachment to proteins factor 3; Involved in the lipid remodeling steps of GPI-anchor maturation; Belongs to the PGAP3 family.
    
 
 0.590
MLC1
Modulator of VRAC current 1.
      
 0.560
MFSD11
Major facilitator superfamily domain containing 11.
   
  
 0.551
METTL23
Uncharacterized protein.
      
 0.550
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.