STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TRAF4TNF receptor associated factor 4. (195 aa)    
Predicted Functional Partners:
TNFRSF25
TNF receptor superfamily member 25.
    
 
 0.611
ERN2
Endoplasmic reticulum to nucleus signaling 2.
   
 
 0.604
TNFSF9
TNF superfamily member 9; Belongs to the tumor necrosis factor family.
      
 0.604
IRAK4
Interleukin 1 receptor associated kinase 4.
   
 
 0.580
HIKESHI
Heat shock protein nuclear import factor hikeshi.
      
 0.570
IRAK2
Interleukin 1 receptor associated kinase 2.
   
 
 0.557
TRADD
TNFRSF1A associated via death domain.
    
 
 0.551
IL17RC
Interleukin 17 receptor C.
      
 0.549
IRAK3
Interleukin 1 receptor associated kinase 3.
   
 
 0.541
BIRC6
Baculoviral IAP repeat containing 6.
    
 
 0.536
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.