STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ERCC4ERCC excision repair 4, endonuclease catalytic subunit. (902 aa)    
Predicted Functional Partners:
ERCC1
ERCC excision repair 1, endonuclease non-catalytic subunit.
   
 0.995
SLX4
SLX4 structure-specific endonuclease subunit.
   
 0.992
XPA
XPA, DNA damage recognition and repair factor.
    
 0.986
MUS81
MUS81 structure-specific endonuclease subunit.
   
 0.942
FANCF
FA complementation group F.
    
 0.942
FAAP24
FA core complex associated protein 24.
   
 0.939
ERCC2
ERCC excision repair 2, TFIIH core complex helicase subunit.
   
 0.934
ENSCAFP00000062039
Uncharacterized protein.
   
 
 0.930
FANCC
FA complementation group C.
   
 0.929
ERCC3
ERCC excision repair 3, TFIIH core complex helicase subunit.
   
 0.922
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.