STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NFIANuclear factor 1; Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. (545 aa)    
Predicted Functional Partners:
NF1
Neurofibromin 1.
   
  
 0.620
NAGS
N-acetylglutamate synthase.
      
 0.560
SEMA3E
Semaphorin 3E; Belongs to the semaphorin family.
      
 0.533
VRK2
VRK serine/threonine kinase 2.
      
 0.468
RAB14
RAB14, member RAS oncogene family.
   
  
 0.464
AGAP1
ArfGAP with GTPase domain, ankyrin repeat and PH domain 1.
   
  
 0.454
GSX1
GS homeobox 1.
    
 
 0.442
TOM1L2
Target of myb1 like 2 membrane trafficking protein.
   
  
 0.441
VPS50
VPS50 subunit of EARP/GARPII complex.
      
 0.440
OSR2
Odd-skipped related transciption factor 2.
   
 
 0.439
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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