| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SMAD2 | SMAD3 | ENSCAFP00000065569 | ENSCAFP00000025647 | Mothers against decapentaplegic homolog. | Mothers against decapentaplegic homolog. | 0.997 |
| SMAD2 | SMAD4 | ENSCAFP00000065569 | ENSCAFP00000052646 | Mothers against decapentaplegic homolog. | Mothers against decapentaplegic homolog. | 0.999 |
| SMAD2 | SMAD5 | ENSCAFP00000065569 | ENSCAFP00000001536 | Mothers against decapentaplegic homolog. | Mothers against decapentaplegic homolog. | 0.976 |
| SMAD2 | SMAD6 | ENSCAFP00000065569 | ENSCAFP00000025538 | Mothers against decapentaplegic homolog. | Mothers against decapentaplegic homolog. | 0.994 |
| SMAD2 | SMAD7 | ENSCAFP00000065569 | ENSCAFP00000028133 | Mothers against decapentaplegic homolog. | Mothers against decapentaplegic homolog. | 0.973 |
| SMAD2 | SMURF1 | ENSCAFP00000065569 | ENSCAFP00000022329 | Mothers against decapentaplegic homolog. | SMAD specific E3 ubiquitin protein ligase 1. | 0.810 |
| SMAD2 | SMURF2 | ENSCAFP00000065569 | ENSCAFP00000049702 | Mothers against decapentaplegic homolog. | E3 ubiquitin-protein ligase. | 0.986 |
| SMAD2 | TGFBR1 | ENSCAFP00000065569 | ENSCAFP00000040830 | Mothers against decapentaplegic homolog. | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | 0.994 |
| SMAD2 | TGFBR2 | ENSCAFP00000065569 | ENSCAFP00000063016 | Mothers against decapentaplegic homolog. | TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] | 0.987 |
| SMAD2 | YAP1 | ENSCAFP00000065569 | ENSCAFP00000038782 | Mothers against decapentaplegic homolog. | Yes associated protein 1. | 0.936 |
| SMAD3 | SMAD2 | ENSCAFP00000025647 | ENSCAFP00000065569 | Mothers against decapentaplegic homolog. | Mothers against decapentaplegic homolog. | 0.997 |
| SMAD3 | SMAD4 | ENSCAFP00000025647 | ENSCAFP00000052646 | Mothers against decapentaplegic homolog. | Mothers against decapentaplegic homolog. | 0.999 |
| SMAD3 | SMAD5 | ENSCAFP00000025647 | ENSCAFP00000001536 | Mothers against decapentaplegic homolog. | Mothers against decapentaplegic homolog. | 0.976 |
| SMAD3 | SMAD6 | ENSCAFP00000025647 | ENSCAFP00000025538 | Mothers against decapentaplegic homolog. | Mothers against decapentaplegic homolog. | 0.994 |
| SMAD3 | SMAD7 | ENSCAFP00000025647 | ENSCAFP00000028133 | Mothers against decapentaplegic homolog. | Mothers against decapentaplegic homolog. | 0.971 |
| SMAD3 | SMURF1 | ENSCAFP00000025647 | ENSCAFP00000022329 | Mothers against decapentaplegic homolog. | SMAD specific E3 ubiquitin protein ligase 1. | 0.780 |
| SMAD3 | SMURF2 | ENSCAFP00000025647 | ENSCAFP00000049702 | Mothers against decapentaplegic homolog. | E3 ubiquitin-protein ligase. | 0.909 |
| SMAD3 | TGFBR1 | ENSCAFP00000025647 | ENSCAFP00000040830 | Mothers against decapentaplegic homolog. | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | 0.994 |
| SMAD3 | TGFBR2 | ENSCAFP00000025647 | ENSCAFP00000063016 | Mothers against decapentaplegic homolog. | TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] | 0.972 |
| SMAD3 | YAP1 | ENSCAFP00000025647 | ENSCAFP00000038782 | Mothers against decapentaplegic homolog. | Yes associated protein 1. | 0.943 |
