DAPK3 protein (Canis lupus familiaris) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

DAPK3

Death associated protein kinase 3; Belongs to the protein kinase superfamily. (454 aa)

Predicted Functional Partners:

BECN1

0.925

MAPK1

0.917

BECN2

0.913

DAPK1

0.905

DAPK2

0.901

ENSCAFP00000054801

0.731

LUZP1

0.717

ENSCAFP00000059765

0.717

ENSCAFP00000061757

0.698

P2RX6

0.622

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BECN1	BECN2	ENSCAFP00000047143	ENSCAFP00000023183	Beclin 1.	Beclin 2.	0.905
BECN1	DAPK1	ENSCAFP00000047143	ENSCAFP00000001889	Beclin 1.	Death associated protein kinase 1.	0.944
BECN1	DAPK2	ENSCAFP00000047143	ENSCAFP00000035631	Beclin 1.	Death associated protein kinase 2; Belongs to the protein kinase superfamily.	0.937
BECN1	DAPK3	ENSCAFP00000047143	ENSCAFP00000028273	Beclin 1.	Death associated protein kinase 3; Belongs to the protein kinase superfamily.	0.925
BECN2	BECN1	ENSCAFP00000023183	ENSCAFP00000047143	Beclin 2.	Beclin 1.	0.905
BECN2	DAPK1	ENSCAFP00000023183	ENSCAFP00000001889	Beclin 2.	Death associated protein kinase 1.	0.922
BECN2	DAPK2	ENSCAFP00000023183	ENSCAFP00000035631	Beclin 2.	Death associated protein kinase 2; Belongs to the protein kinase superfamily.	0.913
BECN2	DAPK3	ENSCAFP00000023183	ENSCAFP00000028273	Beclin 2.	Death associated protein kinase 3; Belongs to the protein kinase superfamily.	0.913
DAPK1	BECN1	ENSCAFP00000001889	ENSCAFP00000047143	Death associated protein kinase 1.	Beclin 1.	0.944
DAPK1	BECN2	ENSCAFP00000001889	ENSCAFP00000023183	Death associated protein kinase 1.	Beclin 2.	0.922
DAPK1	DAPK2	ENSCAFP00000001889	ENSCAFP00000035631	Death associated protein kinase 1.	Death associated protein kinase 2; Belongs to the protein kinase superfamily.	0.907
DAPK1	DAPK3	ENSCAFP00000001889	ENSCAFP00000028273	Death associated protein kinase 1.	Death associated protein kinase 3; Belongs to the protein kinase superfamily.	0.905
DAPK1	LUZP1	ENSCAFP00000001889	ENSCAFP00000059336	Death associated protein kinase 1.	Leucine zipper protein 1.	0.538
DAPK1	MAPK1	ENSCAFP00000001889	ENSCAFP00000030998	Death associated protein kinase 1.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.917
DAPK2	BECN1	ENSCAFP00000035631	ENSCAFP00000047143	Death associated protein kinase 2; Belongs to the protein kinase superfamily.	Beclin 1.	0.937
DAPK2	BECN2	ENSCAFP00000035631	ENSCAFP00000023183	Death associated protein kinase 2; Belongs to the protein kinase superfamily.	Beclin 2.	0.913
DAPK2	DAPK1	ENSCAFP00000035631	ENSCAFP00000001889	Death associated protein kinase 2; Belongs to the protein kinase superfamily.	Death associated protein kinase 1.	0.907
DAPK2	DAPK3	ENSCAFP00000035631	ENSCAFP00000028273	Death associated protein kinase 2; Belongs to the protein kinase superfamily.	Death associated protein kinase 3; Belongs to the protein kinase superfamily.	0.901
DAPK2	ENSCAFP00000054801	ENSCAFP00000035631	ENSCAFP00000054801	Death associated protein kinase 2; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.704
DAPK2	ENSCAFP00000059765	ENSCAFP00000035631	ENSCAFP00000059765	Death associated protein kinase 2; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.686