STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ZNF185Zinc finger protein 185 with LIM domain. (688 aa)    
Predicted Functional Partners:
DMAC1
Distal membrane arm assembly complex 1.
      
 0.676
CSRNP1
Cysteine and serine rich nuclear protein 1.
   
  
 0.648
DUSP3
Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.
      
 0.647
GUCY1A1
Guanylate cyclase soluble subunit alpha-1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
      
 0.621
UBFD1
Ubiquitin family domain containing 1.
   
  
 0.606
ENSCAFP00000059052
Ubiquitin-like domain-containing protein.
      
 0.605
KLHDC4
Kelch domain containing 4.
   
  
 0.582
TMEM41B
Transmembrane protein 41B.
      
 0.570
SYTL3
Synaptotagmin like 3.
      
 0.564
ARMC7
Armadillo repeat containing 7.
   
  
 0.564
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
Server load: low (10%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.