STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC489591Protein kinase domain-containing protein. (748 aa)    
Predicted Functional Partners:
CCDC124
Coiled-coil domain containing 124.
      
 0.623
AURKAIP1
Aurora kinase A interacting protein 1.
      
 0.623
TUBGCP2
Gamma-tubulin complex component; Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome; Belongs to the TUBGCP family.
      
 0.564
NDC80
NDC80 kinetochore complex component.
   
  
 0.559
CDK1
Cyclin dependent kinase 1; Belongs to the protein kinase superfamily.
   
0.553
CDKN3
Cyclin-dependent kinase inhibitor 3; May play a role in cell cycle regulation. Dual specificity phosphatase active toward substrates containing either phosphotyrosine or phosphoserine residues.
   
  
 0.549
CEP131
Centrosomal protein 131.
    
 0.547
CSNK1D
Casein kinase 1 delta.
     
 0.539
CCDC77
Coiled-coil domain containing 77.
      
 0.539
CSNK1E
Casein kinase 1 epsilon; Belongs to the protein kinase superfamily.
     
0.539
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.