STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACAP3ArfGAP with coiled-coil, ankyrin repeat and PH domains 3. (832 aa)    
Predicted Functional Partners:
RAB35
RAB35, member RAS oncogene family.
   
 
 0.695
UBE2J2
Ubiquitin conjugating enzyme E2 J2.
 
    
 0.686
SCNN1D
Sodium channel epithelial 1 delta subunit; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.
   
  
 0.650
APPL2
Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2.
   
 
0.600
APPL1
Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1.
   
 
0.600
AGFG2
ArfGAP with FG repeats 2.
      
 0.575
ZNF410
Zinc finger protein 410.
      
 0.559
NEMF
Nuclear export mediator factor.
      
 0.515
ATP6V1F
V-type proton ATPase subunit F; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.
      
 0.491
CHD2
Chromodomain helicase DNA binding protein 2.
   
 
 0.471
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
Server load: low (26%) [HD]