Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CTNNB1 | FZD7 | ENSCAFP00000007783 | ENSCAFP00000031132 | Catenin beta-1; Key downstream component of the canonical Wnt signaling pathway. In the absence of Wnt, forms a complex with AXIN1, AXIN2, APC, CSNK1A1 and GSK3B that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of CTNNB1 via BTRC and its subsequent degradation by the proteasome. In the presence of the Wnt ligand, CTNNB1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activation of Wnt responsive genes. Involved in the regulation of cell adhesion, as compone [...] | Frizzled class receptor 7; Belongs to the G-protein coupled receptor Fz/Smo family. | 0.618 |
| CTNNB1 | JUP | ENSCAFP00000007783 | ENSCAFP00000023403 | Catenin beta-1; Key downstream component of the canonical Wnt signaling pathway. In the absence of Wnt, forms a complex with AXIN1, AXIN2, APC, CSNK1A1 and GSK3B that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of CTNNB1 via BTRC and its subsequent degradation by the proteasome. In the presence of the Wnt ligand, CTNNB1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activation of Wnt responsive genes. Involved in the regulation of cell adhesion, as compone [...] | Uncharacterized protein. | 0.788 |
| CTNNB1 | RHOA | ENSCAFP00000007783 | ENSCAFP00000030438 | Catenin beta-1; Key downstream component of the canonical Wnt signaling pathway. In the absence of Wnt, forms a complex with AXIN1, AXIN2, APC, CSNK1A1 and GSK3B that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of CTNNB1 via BTRC and its subsequent degradation by the proteasome. In the presence of the Wnt ligand, CTNNB1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activation of Wnt responsive genes. Involved in the regulation of cell adhesion, as compone [...] | Transforming protein RhoA; Small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. Mainly associated with cytoskeleton organization, in active state binds to a variety of effector proteins to regulate cellular responses such cytoskeletal dynamics, cell migration and cell cycle. Regulates a signal transduction pathway linking plasma membrane receptors to the assembly of focal adhesions and actin stress fibers. Involved in a microtubule-dependent signal that is required for the myosin contractile ring formation during cell cycle cytokinesis. Plays an essent [...] | 0.648 |
| CTNNB1 | TAX1BP3 | ENSCAFP00000007783 | ENSCAFP00000028582 | Catenin beta-1; Key downstream component of the canonical Wnt signaling pathway. In the absence of Wnt, forms a complex with AXIN1, AXIN2, APC, CSNK1A1 and GSK3B that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of CTNNB1 via BTRC and its subsequent degradation by the proteasome. In the presence of the Wnt ligand, CTNNB1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activation of Wnt responsive genes. Involved in the regulation of cell adhesion, as compone [...] | Tax1-binding protein 3; May regulate a number of protein-protein interactions by competing for PDZ domain binding sites. | 0.686 |
| DAAM1 | JUP | ENSCAFP00000043921 | ENSCAFP00000023403 | Dishevelled associated activator of morphogenesis 1. | Uncharacterized protein. | 0.426 |
| DAAM1 | RHOA | ENSCAFP00000043921 | ENSCAFP00000030438 | Dishevelled associated activator of morphogenesis 1. | Transforming protein RhoA; Small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. Mainly associated with cytoskeleton organization, in active state binds to a variety of effector proteins to regulate cellular responses such cytoskeletal dynamics, cell migration and cell cycle. Regulates a signal transduction pathway linking plasma membrane receptors to the assembly of focal adhesions and actin stress fibers. Involved in a microtubule-dependent signal that is required for the myosin contractile ring formation during cell cycle cytokinesis. Plays an essent [...] | 0.952 |
| DAAM1 | RTKN | ENSCAFP00000043921 | ENSCAFP00000012548 | Dishevelled associated activator of morphogenesis 1. | Rhotekin. | 0.400 |
| DAAM1 | TAX1BP3 | ENSCAFP00000043921 | ENSCAFP00000028582 | Dishevelled associated activator of morphogenesis 1. | Tax1-binding protein 3; May regulate a number of protein-protein interactions by competing for PDZ domain binding sites. | 0.517 |
| DNAJC22 | TAX1BP3 | ENSCAFP00000012612 | ENSCAFP00000028582 | DnaJ heat shock protein family (Hsp40) member C22. | Tax1-binding protein 3; May regulate a number of protein-protein interactions by competing for PDZ domain binding sites. | 0.534 |
| DNAJC5B | TAX1BP3 | ENSCAFP00000059840 | ENSCAFP00000028582 | DnaJ heat shock protein family (Hsp40) member C5 beta. | Tax1-binding protein 3; May regulate a number of protein-protein interactions by competing for PDZ domain binding sites. | 0.637 |
| FZD7 | CTNNB1 | ENSCAFP00000031132 | ENSCAFP00000007783 | Frizzled class receptor 7; Belongs to the G-protein coupled receptor Fz/Smo family. | Catenin beta-1; Key downstream component of the canonical Wnt signaling pathway. In the absence of Wnt, forms a complex with AXIN1, AXIN2, APC, CSNK1A1 and GSK3B that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of CTNNB1 via BTRC and its subsequent degradation by the proteasome. In the presence of the Wnt ligand, CTNNB1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activation of Wnt responsive genes. Involved in the regulation of cell adhesion, as compone [...] | 0.618 |
| FZD7 | TAX1BP3 | ENSCAFP00000031132 | ENSCAFP00000028582 | Frizzled class receptor 7; Belongs to the G-protein coupled receptor Fz/Smo family. | Tax1-binding protein 3; May regulate a number of protein-protein interactions by competing for PDZ domain binding sites. | 0.670 |
| JUP | CTNNB1 | ENSCAFP00000023403 | ENSCAFP00000007783 | Uncharacterized protein. | Catenin beta-1; Key downstream component of the canonical Wnt signaling pathway. In the absence of Wnt, forms a complex with AXIN1, AXIN2, APC, CSNK1A1 and GSK3B that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of CTNNB1 via BTRC and its subsequent degradation by the proteasome. In the presence of the Wnt ligand, CTNNB1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activation of Wnt responsive genes. Involved in the regulation of cell adhesion, as compone [...] | 0.788 |
| JUP | DAAM1 | ENSCAFP00000023403 | ENSCAFP00000043921 | Uncharacterized protein. | Dishevelled associated activator of morphogenesis 1. | 0.426 |
| JUP | RHOA | ENSCAFP00000023403 | ENSCAFP00000030438 | Uncharacterized protein. | Transforming protein RhoA; Small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. Mainly associated with cytoskeleton organization, in active state binds to a variety of effector proteins to regulate cellular responses such cytoskeletal dynamics, cell migration and cell cycle. Regulates a signal transduction pathway linking plasma membrane receptors to the assembly of focal adhesions and actin stress fibers. Involved in a microtubule-dependent signal that is required for the myosin contractile ring formation during cell cycle cytokinesis. Plays an essent [...] | 0.474 |
| JUP | RTKN | ENSCAFP00000023403 | ENSCAFP00000012548 | Uncharacterized protein. | Rhotekin. | 0.437 |
| JUP | TAX1BP3 | ENSCAFP00000023403 | ENSCAFP00000028582 | Uncharacterized protein. | Tax1-binding protein 3; May regulate a number of protein-protein interactions by competing for PDZ domain binding sites. | 0.604 |
| NFAT5 | TAX1BP1 | ENSCAFP00000030051 | ENSCAFP00000004461 | Nuclear factor of activated T cells 5. | Tax1 binding protein 1. | 0.420 |
| NFAT5 | TAX1BP3 | ENSCAFP00000030051 | ENSCAFP00000028582 | Nuclear factor of activated T cells 5. | Tax1-binding protein 3; May regulate a number of protein-protein interactions by competing for PDZ domain binding sites. | 0.518 |
| RHOA | CTNNB1 | ENSCAFP00000030438 | ENSCAFP00000007783 | Transforming protein RhoA; Small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. Mainly associated with cytoskeleton organization, in active state binds to a variety of effector proteins to regulate cellular responses such cytoskeletal dynamics, cell migration and cell cycle. Regulates a signal transduction pathway linking plasma membrane receptors to the assembly of focal adhesions and actin stress fibers. Involved in a microtubule-dependent signal that is required for the myosin contractile ring formation during cell cycle cytokinesis. Plays an essent [...] | Catenin beta-1; Key downstream component of the canonical Wnt signaling pathway. In the absence of Wnt, forms a complex with AXIN1, AXIN2, APC, CSNK1A1 and GSK3B that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of CTNNB1 via BTRC and its subsequent degradation by the proteasome. In the presence of the Wnt ligand, CTNNB1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activation of Wnt responsive genes. Involved in the regulation of cell adhesion, as compone [...] | 0.648 |
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