Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CDC42-2 | PARD3 | ENSCAFP00000060180 | ENSCAFP00000005582 | Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...] | Par-3 family cell polarity regulator. | 0.940 |
| CDC42-2 | PARD6A | ENSCAFP00000060180 | ENSCAFP00000040187 | Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...] | Par-6 family cell polarity regulator alpha. | 0.973 |
| CDC42-2 | PARD6G | ENSCAFP00000060180 | ENSCAFP00000000006 | Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...] | Par-6 family cell polarity regulator gamma. | 0.973 |
| CDC42-2 | PIK3R1 | ENSCAFP00000060180 | ENSCAFP00000011322 | Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...] | Phosphoinositide-3-kinase regulatory subunit 1. | 0.945 |
| CDC42-2 | PRKCZ | ENSCAFP00000060180 | ENSCAFP00000028644 | Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...] | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. | 0.938 |
| CDC42-2 | PTEN | ENSCAFP00000060180 | ENSCAFP00000045099 | Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...] | Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase, removing the phosphate in the D3 position of the inositol ring from phosphatidylinositol 3,4,5-trisphosphate, phosphatidylinositol 3,4- diphosphate, phosphatidylinositol 3-phosphate and inositol 1,3,4,5- tetrakisphosphate with order of substrate preference in vitro PtdIns(3,4,5)P3 > PtdIns(3,4)P2 > PtdIns3P > Ins(1,3,4,5)P4. The lipid phosphatase activity is critical for its tumor [...] | 0.947 |
| CDC42-2 | RAC2 | ENSCAFP00000060180 | ENSCAFP00000002174 | Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...] | Rac family small GTPase 2. | 0.919 |
| CDC42-2 | RAC3 | ENSCAFP00000060180 | ENSCAFP00000008868 | Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...] | Uncharacterized protein. | 0.925 |
| LLGL1 | LLGL2 | ENSCAFP00000027044 | ENSCAFP00000007214 | LLGL scribble cell polarity complex component 1. | LLGL scribble cell polarity complex component 2. | 0.974 |
| LLGL1 | PARD6A | ENSCAFP00000027044 | ENSCAFP00000040187 | LLGL scribble cell polarity complex component 1. | Par-6 family cell polarity regulator alpha. | 0.800 |
| LLGL1 | PARD6G | ENSCAFP00000027044 | ENSCAFP00000000006 | LLGL scribble cell polarity complex component 1. | Par-6 family cell polarity regulator gamma. | 0.734 |
| LLGL1 | PRKCZ | ENSCAFP00000027044 | ENSCAFP00000028644 | LLGL scribble cell polarity complex component 1. | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. | 0.983 |
| LLGL2 | LLGL1 | ENSCAFP00000007214 | ENSCAFP00000027044 | LLGL scribble cell polarity complex component 2. | LLGL scribble cell polarity complex component 1. | 0.974 |
| LLGL2 | PARD3 | ENSCAFP00000007214 | ENSCAFP00000005582 | LLGL scribble cell polarity complex component 2. | Par-3 family cell polarity regulator. | 0.553 |
| LLGL2 | PARD6A | ENSCAFP00000007214 | ENSCAFP00000040187 | LLGL scribble cell polarity complex component 2. | Par-6 family cell polarity regulator alpha. | 0.705 |
| LLGL2 | PARD6G | ENSCAFP00000007214 | ENSCAFP00000000006 | LLGL scribble cell polarity complex component 2. | Par-6 family cell polarity regulator gamma. | 0.770 |
| LLGL2 | PRKCZ | ENSCAFP00000007214 | ENSCAFP00000028644 | LLGL scribble cell polarity complex component 2. | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. | 0.970 |
| PARD3 | CDC42-2 | ENSCAFP00000005582 | ENSCAFP00000060180 | Par-3 family cell polarity regulator. | Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...] | 0.940 |
| PARD3 | LLGL2 | ENSCAFP00000005582 | ENSCAFP00000007214 | Par-3 family cell polarity regulator. | LLGL scribble cell polarity complex component 2. | 0.553 |
| PARD3 | PARD6A | ENSCAFP00000005582 | ENSCAFP00000040187 | Par-3 family cell polarity regulator. | Par-6 family cell polarity regulator alpha. | 0.987 |
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