STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SKISKI proto-oncogene. (702 aa)    
Predicted Functional Partners:
SMAD4
Mothers against decapentaplegic homolog.
   
 0.976
SMAD3
Mothers against decapentaplegic homolog.
   
 0.906
SMAD2
Mothers against decapentaplegic homolog.
   
 0.904
NCOR1
Nuclear receptor corepressor 1.
   
 0.800
SMAD1
Mothers against decapentaplegic homolog.
   
 0.791
SMAD5
Mothers against decapentaplegic homolog.
   
 0.788
SMAD9
Mothers against decapentaplegic homolog.
   
 0.786
NCOR2
Nuclear receptor corepressor 2.
   
 0.713
INTS8
Integrator complex subunit 8.
   
 
 0.574
SKIL
SKI like proto-oncogene.
    
  
0.567
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.