STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CCDC27Coiled-coil domain containing 27. (685 aa)    
Predicted Functional Partners:
ENSCAFP00000060200
Uncharacterized protein.
 
      0.899
TP73
Tumor protein p73; Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein.
      
 0.851
ENSCAFP00000043906
J domain-containing protein.
      
 0.641
C28H10orf120
Chromosome 28 C10orf120 homolog.
   
  
 0.523
KCTD10
Potassium channel tetramerization domain containing 10.
      
 0.522
SAXO1
Stabilizer of axonemal microtubules 1.
      
 0.517
ADGRV1
Adhesion G protein-coupled receptor V1; Belongs to the G-protein coupled receptor 2 family.
      
 0.515
LYPD4
LY6/PLAUR domain containing 4.
      
 0.515
TRIM35
Tripartite motif containing 35.
      
 0.487
INSL6
Insulin like 6.
   
  
 0.483
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.