STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC491263Beta-lactoglobulin-2; Primary component of whey, it binds retinol and is probably involved in the transport of that molecule; Belongs to the calycin superfamily. Lipocalin family. (250 aa)    
Predicted Functional Partners:
LALBA
Alpha-lactalbumin; Regulatory subunit of lactose synthase, changes the substrate specificity of galactosyltransferase in the mammary gland making glucose a good acceptor substrate for this enzyme. This enables LS to synthesize lactose, the major carbohydrate component of milk. In other tissues, galactosyltransferase transfers galactose onto the N- acetylglucosamine of the oligosaccharide chains in glycoproteins; Belongs to the glycosyl hydrolase 22 family.
   
  
 0.862
LYZL4
Lysozyme like 4.
   
  
 0.771
SPACA3
Sperm acrosome membrane-associated protein 3; Sperm surface membrane protein that may be involved in sperm- egg plasma membrane adhesion and fusion during fertilization. It could be a potential receptor for the egg oligosaccharide residue N- acetylglucosamine, which is present in the extracellular matrix over the egg plasma membrane. The processed form has no detectable bacteriolytic activity in vitro (By similarity).
   
  
 0.743
TOP2B
DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.
   
  
 0.675
CSN3
Kappa-casein; Kappa-casein stabilizes micelle formation, preventing casein precipitation in milk; Belongs to the kappa-casein family.
   
 
 0.671
CSN2
Beta-casein; Important role in determination of the surface properties of the casein micelles.
   
  
 0.601
H9GX31_CANLF
Uncharacterized protein; Belongs to the glycosyl hydrolase 22 family.
   
  
 0.536
LOC480492
Lysozyme B; Belongs to the glycosyl hydrolase 22 family.
   
  
 0.536
LOC100856074
Uncharacterized protein; Belongs to the glycosyl hydrolase 22 family.
   
  
 0.536
ENSCAFP00000062815
Uncharacterized protein; Belongs to the glycosyl hydrolase 22 family.
   
  
 0.536
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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