STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LRIF1Ligand dependent nuclear receptor interacting factor 1. (757 aa)    
Predicted Functional Partners:
SMCHD1
Structural maintenance of chromosomes flexible hinge domain containing 1.
    
 
 0.804
RMND5A
Required for meiotic nuclear division 5 homolog A.
      
 0.679
HERC2
HECT and RLD domain containing E3 ubiquitin protein ligase 2.
      
 0.670
RANBP10
RAN binding protein 10.
      
 0.668
CACYBP
Calcyclin binding protein.
      
 0.636
NEK4
NIMA related kinase 4.
      
 0.563
S100A12
Protein S100; Belongs to the S-100 family.
    
 
 0.521
UNC119
Protein unc-119 homolog A; Involved in synaptic functions in photoreceptor cells, the signal transduction in immune cells as a Src family kinase activator, endosome recycling, the uptake of bacteria and endocytosis, protein trafficking in sensory neurons and as lipid-binding chaperone with specificity for a diverse subset of myristoylated proteins. Specifically binds the myristoyl moiety of a subset of N-terminally myristoylated proteins and is required for their localization. Binds myristoylated GNAT1 and is required for G-protein localization and trafficking in sensory neurons. Proba [...]
      
 0.517
NPHP4
Nephrocystin 4.
      
 0.515
TRAT1
T cell receptor associated transmembrane adaptor 1.
      
 0.514
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.