STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPIRE2Spire type actin nucleation factor 2. (702 aa)    
Predicted Functional Partners:
ZNF276
Zinc finger protein 276.
    
 
 0.861
DEF8
Differentially expressed in FDCP 8 homolog.
      
 0.816
MYO5A
Myosin VA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
   
 
 0.807
FMN1
Formin 1.
    
 
 0.756
FMN2
Formin 2.
    
 
 0.756
DBNDD1
Dysbindin domain containing 1.
   
  
 0.707
VPS9D1
VPS9 domain containing 1.
      
 0.707
GRAP2
GRB2 related adaptor protein 2.
   
 
 0.698
MYO5B
Myosin VB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
   
 
 0.693
OR5K4
Olfactory receptor.
    
 
 0.681
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.