SETX protein (Canis lupus familiaris) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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[Homology]

Score

SETX

Senataxin. (2700 aa)

Predicted Functional Partners:

SCAF8

0.887

SCAF4

0.882

C11H9orf72

0.846

XRN2

0.842

POLR2A

0.840

RAMAC

0.807

RNASEH1

0.806

NIPBL

0.768

ALS2

0.743

VAPB

0.728

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ALS2	C11H9orf72	ENSCAFP00000018218	ENSCAFP00000002503	Alsin Rho guanine nucleotide exchange factor ALS2.	Chromosome 11 C9orf72 homolog.	0.900
ALS2	SETX	ENSCAFP00000018218	ENSCAFP00000029470	Alsin Rho guanine nucleotide exchange factor ALS2.	Senataxin.	0.743
ALS2	VAPB	ENSCAFP00000018218	ENSCAFP00000017842	Alsin Rho guanine nucleotide exchange factor ALS2.	VAMP associated protein B and C.	0.662
C11H9orf72	ALS2	ENSCAFP00000002503	ENSCAFP00000018218	Chromosome 11 C9orf72 homolog.	Alsin Rho guanine nucleotide exchange factor ALS2.	0.900
C11H9orf72	SETX	ENSCAFP00000002503	ENSCAFP00000029470	Chromosome 11 C9orf72 homolog.	Senataxin.	0.846
C11H9orf72	VAPB	ENSCAFP00000002503	ENSCAFP00000017842	Chromosome 11 C9orf72 homolog.	VAMP associated protein B and C.	0.846
NIPBL	SETX	ENSCAFP00000040036	ENSCAFP00000029470	Nipped-B protein.	Senataxin.	0.768
POLR2A	SCAF4	ENSCAFP00000037353	ENSCAFP00000047335	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	SR-related CTD associated factor 4.	0.823
POLR2A	SCAF8	ENSCAFP00000037353	ENSCAFP00000000804	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	SR-related CTD associated factor 8.	0.823
POLR2A	SETX	ENSCAFP00000037353	ENSCAFP00000029470	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	Senataxin.	0.840
POLR2A	XRN2	ENSCAFP00000037353	ENSCAFP00000007767	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	5'-3' exoribonuclease; Possesses 5'->3' exoribonuclease activity. May promote termination of transcription by RNA polymerase II.	0.518
RAMAC	SETX	ENSCAFP00000019430	ENSCAFP00000029470	RNA guanine-7 methyltransferase activating subunit.	Senataxin.	0.807
RAMAC	XRN2	ENSCAFP00000019430	ENSCAFP00000007767	RNA guanine-7 methyltransferase activating subunit.	5'-3' exoribonuclease; Possesses 5'->3' exoribonuclease activity. May promote termination of transcription by RNA polymerase II.	0.429
RNASEH1	SETX	ENSCAFP00000036857	ENSCAFP00000029470	Ribonuclease H1; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.	Senataxin.	0.806
RNASEH1	XRN2	ENSCAFP00000036857	ENSCAFP00000007767	Ribonuclease H1; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.	5'-3' exoribonuclease; Possesses 5'->3' exoribonuclease activity. May promote termination of transcription by RNA polymerase II.	0.413
SCAF4	POLR2A	ENSCAFP00000047335	ENSCAFP00000037353	SR-related CTD associated factor 4.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.823
SCAF4	SETX	ENSCAFP00000047335	ENSCAFP00000029470	SR-related CTD associated factor 4.	Senataxin.	0.882
SCAF4	XRN2	ENSCAFP00000047335	ENSCAFP00000007767	SR-related CTD associated factor 4.	5'-3' exoribonuclease; Possesses 5'->3' exoribonuclease activity. May promote termination of transcription by RNA polymerase II.	0.447
SCAF8	POLR2A	ENSCAFP00000000804	ENSCAFP00000037353	SR-related CTD associated factor 8.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.823
SCAF8	SETX	ENSCAFP00000000804	ENSCAFP00000029470	SR-related CTD associated factor 8.	Senataxin.	0.887