STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ABL1Tyrosine-protein kinase. (1150 aa)    
Predicted Functional Partners:
CRK
CRK proto-oncogene, adaptor protein.
    
0.994
CRKL
CRK like proto-oncogene, adaptor protein.
   
0.979
GRB2
Growth factor receptor bound protein 2.
   
0.976
CBL
Cbl proto-oncogene.
   
 0.975
RIN1
Ras and Rab interactor 1.
   
 0.968
BCR
BCR activator of RhoGEF and GTPase.
    
 0.961
ABI1
Abl interactor 1.
    
 0.952
RB1
RB transcriptional corepressor 1.
   
 0.950
ENAH
ENAH actin regulator.
    
 0.945
ABL2
Tyrosine-protein kinase.
  
0.932
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.