STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DOLPP1Dolichyldiphosphatase 1. (238 aa)    
Predicted Functional Partners:
NUS1
NUS1 dehydrodolichyl diphosphate synthase subunit.
  
 
 0.848
SRD5A3
Steroid 5 alpha-reductase 3.
      
 0.705
ALG5
ALG5 dolichyl-phosphate beta-glucosyltransferase.
  
  
 0.691
DHDDS
Alkyl transferase; Belongs to the UPP synthase family.
  
 
 0.688
ALG6
Alpha-1,3-glucosyltransferase; Belongs to the ALG6/ALG8 glucosyltransferase family.
    
 
 0.683
ALG11
ALG11 alpha-1,2-mannosyltransferase.
  
  
 0.659
ALG13
Uncharacterized protein.
      
 0.626
ALG14
ALG14 UDP-N-acetylglucosaminyltransferase subunit.
    
 
 0.591
DPM1
Dolichol-phosphate mannosyltransferase subunit 1; Transfers mannose from GDP-mannose to dolichol monophosphate to form dolichol phosphate mannose (Dol-P-Man) which is the mannosyl donor in pathways leading to N-glycosylation, glycosyl phosphatidylinositol membrane anchoring, and O-mannosylation of proteins.
     
 0.579
MPDU1
Mannose-P-dolichol utilization defect 1.
   
  
 0.571
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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