STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PKD1L3Polycystin 1 like 3, transient receptor potential channel interacting. (1634 aa)    
Predicted Functional Partners:
PKD2L1
Polycystin 2 like 1, transient receptor potential cation channel.
   
 
0.961
PKD1L2
Polycystin 1 like 2.
 
 
    0.902
TRPM5
Transient receptor potential cation channel subfamily M member 5.
   
  
 0.863
PRSS37
Serine protease 37.
   
  
 0.765
PKD2
Polycystin 2, transient receptor potential cation channel.
    
 
0.730
CALHM1
Calcium homeostasis modulator 1.
   
  
 0.710
PKD2L2
Polycystin 2 like 2, transient receptor potential cation channel.
   
 
0.691
TAS1R3
Taste receptor type 1 member 3; Putative taste receptor. TAS1R1/TAS1R3 responds to the umami taste stimulus (the taste of monosodium glutamate). TAS1R2/TAS1R3 recognizes diverse natural and synthetic sweeteners. TAS1R3 is essential for the recognition and response to the disaccharide trehalose (By similarity). Sequence differences within and between species can significantly influence the selectivity and specificity of taste responses (By similarity).
   
  
 0.688
TAS1R2
Taste receptor type 1 member 2; Putative taste receptor. TAS1R2/TAS1R3 recognizes diverse natural and synthetic sweeteners (By similarity).
   
  
 0.658
TAS1R1
Taste 1 receptor member 1.
   
  
 0.609
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.