STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CDH8Cadherin 8; Cadherins are calcium-dependent cell adhesion proteins. (799 aa)    
Predicted Functional Partners:
SORCS3
Sortilin related VPS10 domain containing receptor 3.
   
 
 0.777
JUP
Uncharacterized protein.
    
 0.745
CTNND1
Catenin delta 1.
   
 0.740
CTNNA1
Catenin alpha 1.
    
 0.658
IGSF21
Immunoglobin superfamily member 21.
   
 
 0.645
KIRREL3
Kirre like nephrin family adhesion molecule 3.
   
 
 0.635
PCDH15
Protocadherin related 15.
   
 
0.632
CDH7
Cadherin 7; Cadherins are calcium-dependent cell adhesion proteins.
  
 
0.600
CDH12
Cadherin 12; Cadherins are calcium-dependent cell adhesion proteins.
   
0.600
CDH9
Cadherin 9; Cadherins are calcium-dependent cell adhesion proteins.
  
 
0.588
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.