STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ARRDC5Arrestin domain containing 5. (419 aa)    
Predicted Functional Partners:
NEDD4
NEDD4 E3 ubiquitin protein ligase.
    
 
 0.767
VPS26C
VPS26 endosomal protein sorting factor C.
      
 0.743
WWP2
E3 ubiquitin-protein ligase.
   
 
 0.725
TXNIP
Thioredoxin interacting protein.
      
 0.692
ZNRF1
Zinc and ring finger 1.
      
 0.661
NUTM1
Uncharacterized protein.
      
 0.609
PHF7
PHD finger protein 7.
   
  
 0.605
TNFRSF1B
TNF receptor superfamily member 1B.
      
 0.604
ADAD2
Adenosine deaminase domain containing 2.
      
 0.602
FBXO47
F-box protein 47.
      
 0.602
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.