FAXC protein (Canis lupus familiaris) - STRING interaction network

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[Homology]

Score

FAXC

Failed axon connections homolog, metaxin like GST domain containing. (409 aa)

Predicted Functional Partners:

COQ3

0.875

PNISR

0.804

FBXL4

0.792

USP45

0.787

DSTYK

0.698

CCNC

0.695

PITPNM2

0.680

QSER1

0.677

TMTC2

0.674

TEX9

0.671

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CCNC	COQ3	ENSCAFP00000005248	ENSCAFP00000005167	Cyclin C; Belongs to the cyclin family.	Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family.	0.647
CCNC	FAXC	ENSCAFP00000005248	ENSCAFP00000030919	Cyclin C; Belongs to the cyclin family.	Failed axon connections homolog, metaxin like GST domain containing.	0.695
CCNC	FBXL4	ENSCAFP00000005248	ENSCAFP00000005165	Cyclin C; Belongs to the cyclin family.	F-box and leucine rich repeat protein 4.	0.655
CCNC	PNISR	ENSCAFP00000005248	ENSCAFP00000005179	Cyclin C; Belongs to the cyclin family.	PNN interacting serine and arginine rich protein.	0.648
CCNC	USP45	ENSCAFP00000005248	ENSCAFP00000041158	Cyclin C; Belongs to the cyclin family.	Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family.	0.453
COQ3	CCNC	ENSCAFP00000005167	ENSCAFP00000005248	Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family.	Cyclin C; Belongs to the cyclin family.	0.647
COQ3	FAXC	ENSCAFP00000005167	ENSCAFP00000030919	Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family.	Failed axon connections homolog, metaxin like GST domain containing.	0.875
COQ3	FBXL4	ENSCAFP00000005167	ENSCAFP00000005165	Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family.	F-box and leucine rich repeat protein 4.	0.744
COQ3	PNISR	ENSCAFP00000005167	ENSCAFP00000005179	Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family.	PNN interacting serine and arginine rich protein.	0.743
COQ3	USP45	ENSCAFP00000005167	ENSCAFP00000041158	Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family.	Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family.	0.720
DSTYK	FAXC	ENSCAFP00000014726	ENSCAFP00000030919	Dual serine/threonine and tyrosine protein kinase; Acts as a positive regulator of ERK phosphorylation downstream of fibroblast growth factor-receptor activation. Involved in the regulation of both caspase-dependent apoptosis and caspase- independent cell death. In the skin, it plays a predominant role in suppressing caspase-dependent apoptosis in response to UV stress in a range of dermal cell types.	Failed axon connections homolog, metaxin like GST domain containing.	0.698
DSTYK	PITPNM2	ENSCAFP00000014726	ENSCAFP00000053689	Dual serine/threonine and tyrosine protein kinase; Acts as a positive regulator of ERK phosphorylation downstream of fibroblast growth factor-receptor activation. Involved in the regulation of both caspase-dependent apoptosis and caspase- independent cell death. In the skin, it plays a predominant role in suppressing caspase-dependent apoptosis in response to UV stress in a range of dermal cell types.	Phosphatidylinositol transfer protein membrane associated 2.	0.684
DSTYK	QSER1	ENSCAFP00000014726	ENSCAFP00000010854	Dual serine/threonine and tyrosine protein kinase; Acts as a positive regulator of ERK phosphorylation downstream of fibroblast growth factor-receptor activation. Involved in the regulation of both caspase-dependent apoptosis and caspase- independent cell death. In the skin, it plays a predominant role in suppressing caspase-dependent apoptosis in response to UV stress in a range of dermal cell types.	Glutamine and serine rich 1.	0.683
DSTYK	TMTC2	ENSCAFP00000014726	ENSCAFP00000048460	Dual serine/threonine and tyrosine protein kinase; Acts as a positive regulator of ERK phosphorylation downstream of fibroblast growth factor-receptor activation. Involved in the regulation of both caspase-dependent apoptosis and caspase- independent cell death. In the skin, it plays a predominant role in suppressing caspase-dependent apoptosis in response to UV stress in a range of dermal cell types.	Transmembrane O-mannosyltransferase targeting cadherins 2.	0.696
FAXC	CCNC	ENSCAFP00000030919	ENSCAFP00000005248	Failed axon connections homolog, metaxin like GST domain containing.	Cyclin C; Belongs to the cyclin family.	0.695
FAXC	COQ3	ENSCAFP00000030919	ENSCAFP00000005167	Failed axon connections homolog, metaxin like GST domain containing.	Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family.	0.875
FAXC	DSTYK	ENSCAFP00000030919	ENSCAFP00000014726	Failed axon connections homolog, metaxin like GST domain containing.	Dual serine/threonine and tyrosine protein kinase; Acts as a positive regulator of ERK phosphorylation downstream of fibroblast growth factor-receptor activation. Involved in the regulation of both caspase-dependent apoptosis and caspase- independent cell death. In the skin, it plays a predominant role in suppressing caspase-dependent apoptosis in response to UV stress in a range of dermal cell types.	0.698
FAXC	FBXL4	ENSCAFP00000030919	ENSCAFP00000005165	Failed axon connections homolog, metaxin like GST domain containing.	F-box and leucine rich repeat protein 4.	0.792
FAXC	PITPNM2	ENSCAFP00000030919	ENSCAFP00000053689	Failed axon connections homolog, metaxin like GST domain containing.	Phosphatidylinositol transfer protein membrane associated 2.	0.680
FAXC	PNISR	ENSCAFP00000030919	ENSCAFP00000005179	Failed axon connections homolog, metaxin like GST domain containing.	PNN interacting serine and arginine rich protein.	0.804