NMS protein (Canis lupus familiaris) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

NMS

Neuromedin S. (147 aa)

Predicted Functional Partners:

NMUR2

0.996

NMUR1

0.965

J9P6U9_CANLF

0.847

NPS

0.822

NPB

0.820

NMB

0.800

KISS1

0.717

PRLH

0.712

GRP

0.675

NTS

0.669

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GRP	KISS1	ENSCAFP00000000137	ENSCAFP00000037810	Gastrin-releasing peptide; Stimulates the release of gastrin and other gastrointestinal hormones (By similarity). Contributes to the perception of prurient stimuli and to the transmission of itch signals in the spinal cord that promote scratching behavior. Contributes primarily to nonhistaminergic itch sensation. Contributes to long-term fear memory, but not normal spatial memory. Contributes to the regulation of food intake (By similarity); Belongs to the bombesin/neuromedin-B/ranatensin family.	Kisspeptin.	0.402
GRP	NMB	ENSCAFP00000000137	ENSCAFP00000036677	Gastrin-releasing peptide; Stimulates the release of gastrin and other gastrointestinal hormones (By similarity). Contributes to the perception of prurient stimuli and to the transmission of itch signals in the spinal cord that promote scratching behavior. Contributes primarily to nonhistaminergic itch sensation. Contributes to long-term fear memory, but not normal spatial memory. Contributes to the regulation of food intake (By similarity); Belongs to the bombesin/neuromedin-B/ranatensin family.	Neuromedin B.	0.973
GRP	NMS	ENSCAFP00000000137	ENSCAFP00000030920	Gastrin-releasing peptide; Stimulates the release of gastrin and other gastrointestinal hormones (By similarity). Contributes to the perception of prurient stimuli and to the transmission of itch signals in the spinal cord that promote scratching behavior. Contributes primarily to nonhistaminergic itch sensation. Contributes to long-term fear memory, but not normal spatial memory. Contributes to the regulation of food intake (By similarity); Belongs to the bombesin/neuromedin-B/ranatensin family.	Neuromedin S.	0.675
GRP	NMUR1	ENSCAFP00000000137	ENSCAFP00000041132	Gastrin-releasing peptide; Stimulates the release of gastrin and other gastrointestinal hormones (By similarity). Contributes to the perception of prurient stimuli and to the transmission of itch signals in the spinal cord that promote scratching behavior. Contributes primarily to nonhistaminergic itch sensation. Contributes to long-term fear memory, but not normal spatial memory. Contributes to the regulation of food intake (By similarity); Belongs to the bombesin/neuromedin-B/ranatensin family.	Neuromedin U receptor 1; Belongs to the G-protein coupled receptor 1 family.	0.528
GRP	NMUR2	ENSCAFP00000000137	ENSCAFP00000026284	Gastrin-releasing peptide; Stimulates the release of gastrin and other gastrointestinal hormones (By similarity). Contributes to the perception of prurient stimuli and to the transmission of itch signals in the spinal cord that promote scratching behavior. Contributes primarily to nonhistaminergic itch sensation. Contributes to long-term fear memory, but not normal spatial memory. Contributes to the regulation of food intake (By similarity); Belongs to the bombesin/neuromedin-B/ranatensin family.	Neuromedin U receptor 2; Belongs to the G-protein coupled receptor 1 family.	0.749
GRP	NPS	ENSCAFP00000000137	ENSCAFP00000040359	Gastrin-releasing peptide; Stimulates the release of gastrin and other gastrointestinal hormones (By similarity). Contributes to the perception of prurient stimuli and to the transmission of itch signals in the spinal cord that promote scratching behavior. Contributes primarily to nonhistaminergic itch sensation. Contributes to long-term fear memory, but not normal spatial memory. Contributes to the regulation of food intake (By similarity); Belongs to the bombesin/neuromedin-B/ranatensin family.	Neuropeptide S.	0.508
GRP	NTS	ENSCAFP00000000137	ENSCAFP00000008959	Gastrin-releasing peptide; Stimulates the release of gastrin and other gastrointestinal hormones (By similarity). Contributes to the perception of prurient stimuli and to the transmission of itch signals in the spinal cord that promote scratching behavior. Contributes primarily to nonhistaminergic itch sensation. Contributes to long-term fear memory, but not normal spatial memory. Contributes to the regulation of food intake (By similarity); Belongs to the bombesin/neuromedin-B/ranatensin family.	Neurotensin/neuromedin N; Neurotensin may play an endocrine or paracrine role in the regulation of fat metabolism. It causes contraction of smooth muscle.	0.854
J9P6U9_CANLF	KISS1	ENSCAFP00000041382	ENSCAFP00000037810	Uncharacterized protein.	Kisspeptin.	0.457
J9P6U9_CANLF	NMS	ENSCAFP00000041382	ENSCAFP00000030920	Uncharacterized protein.	Neuromedin S.	0.847
J9P6U9_CANLF	NMUR1	ENSCAFP00000041382	ENSCAFP00000041132	Uncharacterized protein.	Neuromedin U receptor 1; Belongs to the G-protein coupled receptor 1 family.	0.501
J9P6U9_CANLF	NMUR2	ENSCAFP00000041382	ENSCAFP00000026284	Uncharacterized protein.	Neuromedin U receptor 2; Belongs to the G-protein coupled receptor 1 family.	0.501
J9P6U9_CANLF	NPB	ENSCAFP00000041382	ENSCAFP00000041442	Uncharacterized protein.	Neuropeptide B.	0.981
J9P6U9_CANLF	NPS	ENSCAFP00000041382	ENSCAFP00000040359	Uncharacterized protein.	Neuropeptide S.	0.597
J9P6U9_CANLF	PRLH	ENSCAFP00000041382	ENSCAFP00000018070	Uncharacterized protein.	Prolactin releasing hormone.	0.781
KISS1	GRP	ENSCAFP00000037810	ENSCAFP00000000137	Kisspeptin.	Gastrin-releasing peptide; Stimulates the release of gastrin and other gastrointestinal hormones (By similarity). Contributes to the perception of prurient stimuli and to the transmission of itch signals in the spinal cord that promote scratching behavior. Contributes primarily to nonhistaminergic itch sensation. Contributes to long-term fear memory, but not normal spatial memory. Contributes to the regulation of food intake (By similarity); Belongs to the bombesin/neuromedin-B/ranatensin family.	0.402
KISS1	J9P6U9_CANLF	ENSCAFP00000037810	ENSCAFP00000041382	Kisspeptin.	Uncharacterized protein.	0.457
KISS1	NMB	ENSCAFP00000037810	ENSCAFP00000036677	Kisspeptin.	Neuromedin B.	0.460
KISS1	NMS	ENSCAFP00000037810	ENSCAFP00000030920	Kisspeptin.	Neuromedin S.	0.717
KISS1	NMUR1	ENSCAFP00000037810	ENSCAFP00000041132	Kisspeptin.	Neuromedin U receptor 1; Belongs to the G-protein coupled receptor 1 family.	0.499
KISS1	NMUR2	ENSCAFP00000037810	ENSCAFP00000026284	Kisspeptin.	Neuromedin U receptor 2; Belongs to the G-protein coupled receptor 1 family.	0.499