STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NUDT21Cleavage and polyadenylation specificity factor subunit 5; Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The [...] (227 aa)    
Predicted Functional Partners:
CPSF6
Cleavage and polyadenylation specific factor 6.
   
 0.974
CPSF7
Cleavage and polyadenylation specific factor 7.
   
 0.967
FIP1L1
Factor interacting with PAPOLA and CPSF1.
   
 0.849
NUDT5
Nudix hydrolase 5; Belongs to the Nudix hydrolase family.
   
  
 0.841
NUDT4
Nudix hydrolase 4.
   
  
 0.835
NUDT22
Nudix hydrolase 22.
   
  
 0.830
NUDT18
Nudix hydrolase 18; Belongs to the Nudix hydrolase family.
   
  
 0.825
CPSF4
Cleavage and polyadenylation specific factor 4.
   
 0.822
NUDT2
Nudix hydrolase 2.
   
  
 0.821
NUDT3
Nudix hydrolase 3.
   
  
 0.812
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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