STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DDI1DNA damage inducible 1 homolog 1. (395 aa)    
Predicted Functional Partners:
DDI2
Uncharacterized protein.
  
   
0.790
AASDH
Aminoadipate-semialdehyde dehydrogenase.
   
 
 0.782
RAD23A
RAD23 homolog A, nucleotide excision repair protein.
   
 
 0.689
RAD23B
RAD23 homolog B, nucleotide excision repair protein.
    
 
 0.620
TOP2A
DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.
   
  
 0.572
ULK1
Unc-51 like autophagy activating kinase 1.
    
 
 0.557
ULK2
Unc-51 like autophagy activating kinase 2.
    
 
 0.557
RTF2
Replication termination factor 2.
    
 
 0.516
SERPINB2
Serpin family B member 2; Belongs to the serpin family.
      
 0.515
SDE2
SDE2 telomere maintenance homolog.
      
 0.515
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.