STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
F8A1Uncharacterized protein. (420 aa)    
Predicted Functional Partners:
HTT
Huntingtin.
    
 
 0.904
ANKFY1
Ankyrin repeat and FYVE domain containing 1.
      
 0.586
PIK3C3
Phosphatidylinositol 3-kinase catalytic subunit type 3.
      
 0.499
PIK3CB
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family.
      
 0.483
APPL2
Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2.
      
 0.482
APPL1
Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1.
      
 0.482
ETF1
Uncharacterized protein.
      
 0.412
J9P581_CANLF
eRF1_1 domain-containing protein.
      
 0.412
PIK3R1
Phosphoinositide-3-kinase regulatory subunit 1.
      
 0.410
RAB5B
RAB5B, member RAS oncogene family.
    
 
 0.409
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.