STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HOXD12Homeobox D12. (270 aa)    
Predicted Functional Partners:
EVX2
Even-skipped homeobox 2.
   
 
0.542
RPP30
Ribonuclease P/MRP subunit p30.
      
 0.541
HAND2
Heart and neural crest derivatives expressed 2.
    
 
 0.537
MCPH1
Microcephalin 1.
      
 0.518
SMARCC1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1.
   
  
 0.518
IDH2
Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family.
   
  
 0.481
DCAF6
DDB1 and CUL4 associated factor 6.
      
 0.433
RNF121
Ring finger protein 121.
      
 0.432
HOXB2
Homeobox B2.
  
 
 
0.425
DLX4
Distal-less homeobox 4.
    
 
0.402
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.