STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GLRX5Glutaredoxin 5. (204 aa)    
Predicted Functional Partners:
BOLA1
BolA family member 1; Belongs to the BolA/IbaG family.
   
 
 0.970
ABCB7
ATP binding cassette subfamily B member 7.
   
 
 0.869
ENSCAFP00000063468
Uncharacterized protein; Belongs to the BolA/IbaG family.
    
 
 0.816
ISCA2
Fe-S_biosyn domain-containing protein.
   
 0.806
SLC25A38
Mitochondrial glycine transporter; Mitochondrial glycine transporter that imports glycine into the mitochondrial matrix. Plays an important role in providing glycine for the first enzymatic step in heme biosynthesis, the condensation of glycine with succinyl-CoA to produce 5-aminolevulinate (ALA) in the miochondrial matrix. Required during erythropoiesis. Belongs to the mitochondrial carrier (TC 2.A.29) family. SLC25A38 subfamily.
   
  
 0.768
IBA57
Iron-sulfur cluster assembly factor IBA57.
    
 
 0.749
GLRX3
Glutaredoxin 3.
   
  
 0.735
ENSCAFP00000061052
Fe-S_biosyn domain-containing protein.
   
 0.730
FECH
Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX.
   
 
 0.698
HSCB
HscB mitochondrial iron-sulfur cluster cochaperone.
   
 0.667
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.