STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DLX2Distal-less homeobox 2. (334 aa)    
Predicted Functional Partners:
ASCL1
Achaete-scute family bHLH transcription factor 1.
   
  
 0.859
TBR1
T-box brain transcription factor 1.
   
 
 0.830
DLX1
Distal-less homeobox 1.
   
 
0.788
LHX6
LIM homeobox 6.
   
  
 0.771
IRX2
Iroquois homeobox 2.
   
 
 0.751
SOX10
SRY-box transcription factor 10.
    
 
 0.728
IRX1
Iroquois homeobox 1.
   
 
 0.721
SATB2
DNA-binding protein SATB.
      
 0.703
SP9
Sp9 transcription factor.
   
 
 0.689
GAD2
Glutamate decarboxylase 2; Catalyzes the production of GABA.
   
  
 0.673
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.