PCARE protein (Canis lupus familiaris) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

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Gene Fusion

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Experiments

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[Homology]

Score

PCARE

Uncharacterized protein. (1308 aa)

Predicted Functional Partners:

J9P328_CANLF

0.527

VASP

0.527

PCCB

0.518

TENM1

0.495

ABI1

0.450

SHROOM3

0.403

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABI1	J9P328_CANLF	ENSCAFP00000006495	ENSCAFP00000039957	Abl interactor 1.	WH1 domain-containing protein.	0.660
ABI1	PCARE	ENSCAFP00000006495	ENSCAFP00000031832	Abl interactor 1.	Uncharacterized protein.	0.450
ABI1	VASP	ENSCAFP00000006495	ENSCAFP00000064684	Abl interactor 1.	Vasodilator-stimulated phosphoprotein; Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration. VASP promotes actin filament elongation. It protects the barbed end of growing actin filaments against capping and increases the rate of actin polymerization in the presence of capping protein. VASP stimulates actin filament elongation by promoting the transfer of profilin-bound actin monomers onto the barbed end [...]	0.662
J9P328_CANLF	ABI1	ENSCAFP00000039957	ENSCAFP00000006495	WH1 domain-containing protein.	Abl interactor 1.	0.660
J9P328_CANLF	PCARE	ENSCAFP00000039957	ENSCAFP00000031832	WH1 domain-containing protein.	Uncharacterized protein.	0.527
J9P328_CANLF	SHROOM3	ENSCAFP00000039957	ENSCAFP00000053352	WH1 domain-containing protein.	Shroom family member 3.	0.416
PCARE	ABI1	ENSCAFP00000031832	ENSCAFP00000006495	Uncharacterized protein.	Abl interactor 1.	0.450
PCARE	J9P328_CANLF	ENSCAFP00000031832	ENSCAFP00000039957	Uncharacterized protein.	WH1 domain-containing protein.	0.527
PCARE	PCCB	ENSCAFP00000031832	ENSCAFP00000051662	Uncharacterized protein.	Propionyl-CoA carboxylase subunit beta.	0.518
PCARE	SHROOM3	ENSCAFP00000031832	ENSCAFP00000053352	Uncharacterized protein.	Shroom family member 3.	0.403
PCARE	TENM1	ENSCAFP00000031832	ENSCAFP00000027511	Uncharacterized protein.	Teneurin transmembrane protein 1.	0.495
PCARE	VASP	ENSCAFP00000031832	ENSCAFP00000064684	Uncharacterized protein.	Vasodilator-stimulated phosphoprotein; Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration. VASP promotes actin filament elongation. It protects the barbed end of growing actin filaments against capping and increases the rate of actin polymerization in the presence of capping protein. VASP stimulates actin filament elongation by promoting the transfer of profilin-bound actin monomers onto the barbed end [...]	0.527
PCCB	PCARE	ENSCAFP00000051662	ENSCAFP00000031832	Propionyl-CoA carboxylase subunit beta.	Uncharacterized protein.	0.518
SHROOM3	J9P328_CANLF	ENSCAFP00000053352	ENSCAFP00000039957	Shroom family member 3.	WH1 domain-containing protein.	0.416
SHROOM3	PCARE	ENSCAFP00000053352	ENSCAFP00000031832	Shroom family member 3.	Uncharacterized protein.	0.403
SHROOM3	VASP	ENSCAFP00000053352	ENSCAFP00000064684	Shroom family member 3.	Vasodilator-stimulated phosphoprotein; Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration. VASP promotes actin filament elongation. It protects the barbed end of growing actin filaments against capping and increases the rate of actin polymerization in the presence of capping protein. VASP stimulates actin filament elongation by promoting the transfer of profilin-bound actin monomers onto the barbed end [...]	0.419
TENM1	PCARE	ENSCAFP00000027511	ENSCAFP00000031832	Teneurin transmembrane protein 1.	Uncharacterized protein.	0.495
VASP	ABI1	ENSCAFP00000064684	ENSCAFP00000006495	Vasodilator-stimulated phosphoprotein; Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration. VASP promotes actin filament elongation. It protects the barbed end of growing actin filaments against capping and increases the rate of actin polymerization in the presence of capping protein. VASP stimulates actin filament elongation by promoting the transfer of profilin-bound actin monomers onto the barbed end [...]	Abl interactor 1.	0.662
VASP	PCARE	ENSCAFP00000064684	ENSCAFP00000031832	Vasodilator-stimulated phosphoprotein; Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration. VASP promotes actin filament elongation. It protects the barbed end of growing actin filaments against capping and increases the rate of actin polymerization in the presence of capping protein. VASP stimulates actin filament elongation by promoting the transfer of profilin-bound actin monomers onto the barbed end [...]	Uncharacterized protein.	0.527
VASP	SHROOM3	ENSCAFP00000064684	ENSCAFP00000053352	Vasodilator-stimulated phosphoprotein; Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration. VASP promotes actin filament elongation. It protects the barbed end of growing actin filaments against capping and increases the rate of actin polymerization in the presence of capping protein. VASP stimulates actin filament elongation by promoting the transfer of profilin-bound actin monomers onto the barbed end [...]	Shroom family member 3.	0.419