node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ARHGDIA | ARHGDIB | ENSCAFP00000065885 | ENSCAFP00000018985 | Rho GDP dissociation inhibitor alpha. | Rho GDP dissociation inhibitor beta. | 0.903 |
ARHGDIA | RAC1 | ENSCAFP00000065885 | ENSCAFP00000032062 | Rho GDP dissociation inhibitor alpha. | Ras-related C3 botulinum toxin substrate 1; Plasma membrane-associated small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate cellular responses such as secretory processes, phagocytosis of apoptotic cells, epithelial cell polarization, neurons adhesion, migration and differentiation, and growth-factor induced formation of membrane ruffles. Rac1 p21/rho GDI heterodimer is the active component of the cytosolic factor sigma 1, which is involved in stimulation of the NADPH oxidase activity [...] | 0.907 |
ARHGDIB | ARHGDIA | ENSCAFP00000018985 | ENSCAFP00000065885 | Rho GDP dissociation inhibitor beta. | Rho GDP dissociation inhibitor alpha. | 0.903 |
ARHGDIB | RAC1 | ENSCAFP00000018985 | ENSCAFP00000032062 | Rho GDP dissociation inhibitor beta. | Ras-related C3 botulinum toxin substrate 1; Plasma membrane-associated small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate cellular responses such as secretory processes, phagocytosis of apoptotic cells, epithelial cell polarization, neurons adhesion, migration and differentiation, and growth-factor induced formation of membrane ruffles. Rac1 p21/rho GDI heterodimer is the active component of the cytosolic factor sigma 1, which is involved in stimulation of the NADPH oxidase activity [...] | 0.897 |
DOCK2 | RAC1 | ENSCAFP00000024998 | ENSCAFP00000032062 | Dedicator of cytokinesis 2; Belongs to the DOCK family. | Ras-related C3 botulinum toxin substrate 1; Plasma membrane-associated small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate cellular responses such as secretory processes, phagocytosis of apoptotic cells, epithelial cell polarization, neurons adhesion, migration and differentiation, and growth-factor induced formation of membrane ruffles. Rac1 p21/rho GDI heterodimer is the active component of the cytosolic factor sigma 1, which is involved in stimulation of the NADPH oxidase activity [...] | 0.840 |
DOCK2 | VAV1 | ENSCAFP00000024998 | ENSCAFP00000027443 | Dedicator of cytokinesis 2; Belongs to the DOCK family. | Vav guanine nucleotide exchange factor 1. | 0.651 |
DOCK2 | VAV2 | ENSCAFP00000024998 | ENSCAFP00000063386 | Dedicator of cytokinesis 2; Belongs to the DOCK family. | Vav guanine nucleotide exchange factor 2. | 0.665 |
ITSN2 | LOC100856635 | ENSCAFP00000006002 | ENSCAFP00000014017 | Intersectin 2. | Uncharacterized protein. | 0.623 |
ITSN2 | PAK1 | ENSCAFP00000006002 | ENSCAFP00000044903 | Intersectin 2. | Non-specific serine/threonine protein kinase. | 0.471 |
ITSN2 | PAK3 | ENSCAFP00000006002 | ENSCAFP00000007390 | Intersectin 2. | P21 (RAC1) activated kinase 3. | 0.471 |
ITSN2 | RAC1 | ENSCAFP00000006002 | ENSCAFP00000032062 | Intersectin 2. | Ras-related C3 botulinum toxin substrate 1; Plasma membrane-associated small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate cellular responses such as secretory processes, phagocytosis of apoptotic cells, epithelial cell polarization, neurons adhesion, migration and differentiation, and growth-factor induced formation of membrane ruffles. Rac1 p21/rho GDI heterodimer is the active component of the cytosolic factor sigma 1, which is involved in stimulation of the NADPH oxidase activity [...] | 0.833 |
KALRN | PAK1 | ENSCAFP00000018209 | ENSCAFP00000044903 | Kalirin RhoGEF kinase. | Non-specific serine/threonine protein kinase. | 0.545 |
KALRN | RAC1 | ENSCAFP00000018209 | ENSCAFP00000032062 | Kalirin RhoGEF kinase. | Ras-related C3 botulinum toxin substrate 1; Plasma membrane-associated small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate cellular responses such as secretory processes, phagocytosis of apoptotic cells, epithelial cell polarization, neurons adhesion, migration and differentiation, and growth-factor induced formation of membrane ruffles. Rac1 p21/rho GDI heterodimer is the active component of the cytosolic factor sigma 1, which is involved in stimulation of the NADPH oxidase activity [...] | 0.890 |
LOC100856635 | ITSN2 | ENSCAFP00000014017 | ENSCAFP00000006002 | Uncharacterized protein. | Intersectin 2. | 0.623 |
LOC100856635 | RAC1 | ENSCAFP00000014017 | ENSCAFP00000032062 | Uncharacterized protein. | Ras-related C3 botulinum toxin substrate 1; Plasma membrane-associated small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate cellular responses such as secretory processes, phagocytosis of apoptotic cells, epithelial cell polarization, neurons adhesion, migration and differentiation, and growth-factor induced formation of membrane ruffles. Rac1 p21/rho GDI heterodimer is the active component of the cytosolic factor sigma 1, which is involved in stimulation of the NADPH oxidase activity [...] | 0.852 |
PAK1 | ITSN2 | ENSCAFP00000044903 | ENSCAFP00000006002 | Non-specific serine/threonine protein kinase. | Intersectin 2. | 0.471 |
PAK1 | KALRN | ENSCAFP00000044903 | ENSCAFP00000018209 | Non-specific serine/threonine protein kinase. | Kalirin RhoGEF kinase. | 0.545 |
PAK1 | PAK3 | ENSCAFP00000044903 | ENSCAFP00000007390 | Non-specific serine/threonine protein kinase. | P21 (RAC1) activated kinase 3. | 0.906 |
PAK1 | RAC1 | ENSCAFP00000044903 | ENSCAFP00000032062 | Non-specific serine/threonine protein kinase. | Ras-related C3 botulinum toxin substrate 1; Plasma membrane-associated small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate cellular responses such as secretory processes, phagocytosis of apoptotic cells, epithelial cell polarization, neurons adhesion, migration and differentiation, and growth-factor induced formation of membrane ruffles. Rac1 p21/rho GDI heterodimer is the active component of the cytosolic factor sigma 1, which is involved in stimulation of the NADPH oxidase activity [...] | 0.892 |
PAK1 | VAV1 | ENSCAFP00000044903 | ENSCAFP00000027443 | Non-specific serine/threonine protein kinase. | Vav guanine nucleotide exchange factor 1. | 0.584 |